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James F Leckman Selected Research

Tourette Syndrome (Tourette's Syndrome)

1/2021A Phase-2 Pilot Study of a Therapeutic Combination of Δ9-Tetrahydracannabinol and Palmitoylethanolamide for Adults With Tourette's Syndrome.
1/2020Randomized, Sham-Controlled Trial of Real-Time Functional Magnetic Resonance Imaging Neurofeedback for Tics in Adolescents With Tourette Syndrome.
1/2020Autoantibody Biomarkers for Basal Ganglia Encephalitis in Sydenham Chorea and Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infections.
3/2016Deep Brain Stimulation for Tourette Syndrome: Lessons Learned and Future Directions.
1/2016N-Acetylcysteine in the Treatment of Pediatric Tourette Syndrome: Randomized, Double-Blind, Placebo-Controlled Add-On Trial.
1/2016The International Deep Brain Stimulation Registry and Database for Gilles de la Tourette Syndrome: How Does It Work?
8/2015Familial Risks of Tourette Syndrome and Chronic Tic Disorders. A Population-Based Cohort Study.
5/2015Randomized Sham Controlled Double-blind Trial of Repetitive Transcranial Magnetic Stimulation for Adults With Severe Tourette Syndrome.
4/2015Tourette syndrome deep brain stimulation: a review and updated recommendations.
1/2013Neuroendocrine aspects of Tourette syndrome.
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James F Leckman Research Topics

Disease

26Tourette Syndrome (Tourette's Syndrome)
01/2021 - 04/2002
16Tics (Tic)
01/2022 - 01/2005
14Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
10/2022 - 06/2005
11Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
02/2021 - 06/2005
6Tic Disorders (Tic Disorder)
08/2015 - 01/2005
5Autistic Disorder (Autism)
07/2017 - 12/2011
4Streptococcal Infections (Streptococcal Infection)
01/2020 - 01/2006
4Autism Spectrum Disorder
07/2017 - 12/2013
3Infections
01/2020 - 04/2010
3Chorea (Rheumatic Chorea)
01/2020 - 04/2010
2Separation Anxiety (Separation Anxiety Disorder)
01/2017 - 03/2016
2Wounds and Injuries (Trauma)
08/2015 - 06/2014
2Trichotillomania
03/2013 - 10/2007
2Symptom Flare Up
03/2011 - 03/2005
1Suppuration
01/2022
1Encephalitis (Encephalitis, Rasmussen)
01/2020
1Acute Disease
01/2020
1Mumps
01/2017
1Communicable Diseases (Infectious Diseases)
01/2017
1Measles
01/2017
1Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections
10/2016
1Parkinson Disease (Parkinson's Disease)
01/2016
1Movement Disorders (Movement Disorder)
01/2016
1Cognitive Dysfunction
10/2015
1Neurologic Manifestations (Neurological Manifestations)
12/2013
1Rheumatic Fever (Acute Articular Rheumatism)
12/2013
1Neurodevelopmental Disorders
01/2013
1Anxiety Disorders (Anxiety Disorder)
01/2013
1Inflammation (Inflammations)
10/2010
1Multiple Sclerosis
04/2010

Drug/Important Bio-Agent (IBA)

6Oxytocin (Pitocin)FDA LinkGeneric
01/2017 - 01/2013
4Immunoglobulin G (IgG)IBA
01/2020 - 04/2010
4AntibodiesIBA
10/2016 - 06/2005
3EnzymesIBA
01/2020 - 12/2006
3AutoantibodiesIBA
01/2020 - 04/2002
3CytokinesIBA
07/2017 - 03/2005
2A-factor (Streptomyces)IBA
02/2021 - 04/2010
2Biomarkers (Surrogate Marker)IBA
01/2020 - 01/2016
2TubulinIBA
01/2020 - 04/2010
2salicylhydroxamic acid (SHAM)IBA
01/2020 - 05/2015
2ImmunosorbentsIBA
01/2020 - 04/2010
2InterleukinsIBA
07/2017 - 12/2011
2Interleukin-17 (Interleukin 17)IBA
07/2017 - 12/2011
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2017 - 03/2005
2Acetylcysteine (Siran)FDA LinkGeneric
01/2016 - 03/2013
2Antipsychotic Agents (Antipsychotics)IBA
01/2016 - 07/2013
2Antidepressive Agents (Antidepressants)IBA
01/2013 - 08/2004
2InterferonsIBA
12/2011 - 10/2010
2Interleukin-1 (Interleukin 1)IBA
12/2011 - 10/2010
2AntigensIBA
04/2010 - 12/2006
2ParvalbuminsIBA
02/2010 - 09/2005
2Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
10/2007 - 07/2007
1Dronabinol (THC)FDA LinkGeneric
01/2021
1palmidrolIBA
01/2021
1AutoantigensIBA
01/2020
1Dopamine Receptors (Dopamine Receptor)IBA
01/2020
1Interferon-gamma (Interferon, gamma)IBA
07/2017
1Calcium-Binding ProteinsIBA
07/2017
1Interleukin-6 (Interleukin 6)IBA
07/2017
1Interleukin-4 (Interleukin 4)IBA
07/2017
1Interleukin-10 (Interleukin 10)IBA
07/2017
1VaccinesIBA
01/2017
1Rubella VaccineIBA
01/2017
1Intravenous Immunoglobulins (IVIG)FDA Link
10/2016
1ORALIT (ORS)IBA
08/2015
1beta-cyclodextrin tetradecasulfate (CTDS)IBA
08/2015
1Dopamine D2 Receptors (Dopamine D2 Receptor)IBA
12/2013
1EpitopesIBA
12/2013
1Peptides (Polypeptides)IBA
12/2013
1Adrenergic Agonists (Adrenergic Receptor Agonist)IBA
07/2013
1AndrogensIBA
01/2013
1Hormones (Hormone)IBA
01/2013
1SteroidsIBA
01/2013
1Testosterone (Sustanon)FDA Link
01/2013
1KetamineFDA LinkGeneric
12/2012
1Risperidone (Risperdal Consta)FDA LinkGeneric
12/2011
1Interleukin-13IBA
12/2011
1Epidermal Growth Factor (EGF)IBA
12/2011
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
12/2011
1Immunoglobulins (Immunoglobulin)IBA
03/2011
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
11/2010
1Chemotactic FactorsIBA
10/2010
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
10/2010
1Interleukin-2 (IL2)IBA
10/2010
1L 644711 (B-3(+))IBA
06/2010
1Myelin Basic ProteinIBA
04/2010
1Immunoglobulin M (IgM)IBA
04/2010

Therapy/Procedure

6Cognitive Training
01/2021 - 10/2015
6Deep Brain Stimulation
03/2016 - 11/2006
5Therapeutics
01/2022 - 08/2004
4Drug Therapy (Chemotherapy)
09/2011 - 07/2007
2Transcranial Magnetic Stimulation
05/2015 - 10/2007
1Combined Modality Therapy
10/2022
1Neurofeedback
01/2020
1Meditation
01/2019
1Duration of Therapy
09/2015
1Aftercare (After-Treatment)
08/2015
1Drug Prescriptions
06/2014
1Intranasal Administration
12/2013
1Psychology Biofeedback (Biofeedback)
01/2011